ILUSTRA Genetic Risk Test and Inflammation Management Program | ILUSTRA


Inflammation: Is it in Your Employees' DNA? 


Chronic Inflammation is widespread

  • Inflammation is a serious problem and is linked to onset and progression of many chronic inflammatory conditions:
    • Periodontitis
    • Cardiovascular Disease
    • Metabolic Syndrome
    • Diabetes
    • Kidney Disease
    • Rheumatoid Arthritis
    • Adverse Pregnancy Outcomes
  • Up to 86% of healthcare costs are related to conditions associated with inflammation1

1 in 3 people is at risk

1 in 3 people is at risk

  • 1 in 3 people is genetically predisposed to develop severe gum disease and overproduce inflammation
  • Genetics is a leading risk factor along with smoking and diabetes, for identifying who may develop periodontitis2
  • A genetic predisposition to overproduce IL-1 can lead to chronic inflammation
  • Chronic Inflammation can lead to serious medical conditions such as periodontitis, diabetes, heart disease, adverse pregnancy outcomes and many others

Find out more about Chronic Inflammation and its consequences in the following video::

A Simple Solution: The ILUSTRA Inflammation Management Program

Introducing the ILUSTRA Inflammation Management Program to target high risk patients and drive engagement!

Features include:


ILUSTRA Genetic Risk Test

  • Clinically proven to detect an individual’s genetic predisposition for severe periodontal disease caused by overproduction of inflammation
  • A quick, painless cheek swab is all it takes
  • Can easily be administered at clinics, employer health events or at home


Personalized Care Plans

  • Enhanced dental care is a simple and effective way to stay ahead of inflammation and improve chronic diseases
  • Managing periodontitis reduces systemic inflammatory burden and has a demonstrated benefit on systemic health
  • Optimize your existing benefits for targeted employees who can benefit from more personalized care plans


ILUSTRA Engagement Platform

  • Personalized benefit, empowering employees to live healthier with customized health tips and convenient dental reminders
  • 18-month program to drive behavioral change in members by leveraging multiple channels
  • Strengthens the link between members and their dental healthcare professionals, which can improve long-term health outcomes


The clinical efficacy of the ILUSTRA Inflammation Management Program is supported by 23 peer reviewed publications and 5 meta-analyses

Dental intervention reduces CRP1 levels

  • 20% to 39% reduction in patients with moderate to severe periodontitis
  • Reductions in systemic inflammation have been reported even in patients with gingivitis

Treatment of Periodontitis and reduction in inflammation improves glycemic control in patients with Type 2 Diabetes

  • Reduced HbA1c levels by 0.36%
  • Treatment effect equivalent to adding second drug

39% reduction in hospitalization in patients receiving effective periodontal treatment

Please contact us for more information on the studies presented.


  1. Gerteis J et al. Multiple Chronic Conditions Chartbook. AHRQ Publications No. Q14-0038, Rockville, MD: Agency for Healthcare Research and Quality; 2014. Accessed November 18, 2014.
  2. Giannobile WV, Braun TM, Caplis AK, Doucette-Stamm L, Duff GW, Kornman KS. Patient Stratification for Preventative Care in Dentistry. J Dent Res 2013.doi.10.1177/jdr.0022034513492336.
  3. Jeffcoat M, Jeffcoat R, et al. Impact of Periodontal Therapy on General Health Evidence from Insurance Data for Five Systemic Conditions. American Journal of Preventative Medicine 2014;47(2):166-174. (2014).

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